SILVERLINING℠ remains at the forefront of modern psychiatry, offering advanced, evidence-based treatments for patients who have not found relief with traditional options.
Spravato (Esketamine): A New Hope for Treatment-Resistant Depression
Depression is a serious, often life-disrupting condition, and for many individuals, standard antidepressants and therapy are not enough. This is known as treatment-resistant depression, and Spravato (esketamine) offers a promising new path forward for these patients. Spravato is an FDA-approved nasal spray that contains esketamine, a rapid-acting antidepressant specifically designed for adults with treatment-resistant depression or acute suicidal thoughts who have not responded to at least two different antidepressants.
Unlike traditional medications, Spravato works on NMDA receptors in the brain, which play a key role in mood and cognition. By modulating these receptors, Spravato can bring about faster relief of depressive symptoms than many standard treatments.
What to Expect During Treatment
The Spravato treatment course typically begins with an induction phase of twice-weekly sessions for four weeks, followed by a maintenance phase with sessions every two to four weeks. In most cases, treatment is completed in about 14 sessions over approximately 90 days. Because Spravato can cause temporary side effects such as dizziness, nausea, or increased blood pressure, each session includes at least two hours of in-clinic monitoring for your safety.
At SILVERLINING℠, comfort and privacy are integral to your experience. Each patient is provided a private room with a sofa, blankets, pillows, a call button, and easy access to a restroom, helping you feel as relaxed and supported as possible throughout the session.
How Patients Often Feel
Patients’ experiences with Spravato can vary. Some report feelings of deep relaxation or enhanced emotional awareness, while others may experience transient dissociation or “detachment” during the session. As treatment continues and patients become more familiar with the medication’s effects, many describe their sessions as increasingly calm and comfortable.
Insurance and Safety
Spravato is covered by most major insurance plans through a prior authorization process, usually with a manageable copayment. Our team will guide you through each step, explain your coverage, and clarify any out-of-pocket costs before treatment begins.
Spravato represents an important advancement for people living with treatment-resistant depression, offering a new mechanism of action and rapid onset of benefit where other treatments have fallen short. As with any powerful medication, it is essential to work closely with an experienced healthcare provider to determine whether Spravato is appropriate for you. Spravato and other forms of ketamine should never be used at home or without medical supervision, as doing so can be extremely dangerous.
If you are struggling with depression that has not improved despite multiple treatments, we invite you to contact SILVERLINING℠ to learn whether Spravato could be a safe and effective option on your path to recovery.